This matrix explains the different jobs of common acne-oriented ingredient categories. It does not diagnose acne or select medication for an individual.

Category	Typical role	Common downside	Routine note
Salicylic acid	Exfoliating ingredient often used for clogged pores and oily skin	Dryness or irritation	Avoid automatically stacking several exfoliants
Benzoyl peroxide	OTC acne active	Dryness, irritation, fabric bleaching	Follow label directions
Adapalene	Topical retinoid used for acne	Dryness/irritation, especially early in use	Use according to labeling or clinician guidance; pregnancy precautions apply
Moisturizer	Supports tolerability and barrier function	Formula may not suit every skin type	Acne-prone skin does not automatically need to avoid moisturizer

Persistent, painful, scarring, cystic, or suddenly worsening acne deserves individualized assessment.